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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Acifran/1762/50/50 mg
产品编号:1762/50
市  场 价:¥11700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$585.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Acifran/1762/50/50 mg
商品介绍
Description:Hypolipidemicagent;agoNISTfortheGPR109A(HM74A)andGPR109Breceptors
AlternativeNames:AY25712
ChemicalName:4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Hypolipidemicagent.Exhibitshigherpotencythannicotinicacidandclofibrate.FullandpotentagonistatthehumanorphanGPCRHM74A/GPR109AandGPR109B(EC50valuesare1.3 and4.2μMrespectively).ReducesserumtriglyceridesandcirculatingLDL-cholesterolinvivo,withoutaffectingliverweightorliverenzymes.

CompoundLibraries

AcifranisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt218.21
FormulaC12H10O4
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber72420-38-3
PubChemID51576
InChIKeyDFDGRKNOFOJBAJ-UHFFFAOYSA-N
SmilesCC1(OC(=CC1=O)C(O)=O)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.82100
ethanol21.82100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight218.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.58mL22.91mL45.83mL
5mM0.92mL4.58mL9.17mL
10mM0.46mL2.29mL4.58mL
50mM0.09mL0.46mL0.92mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet