DownregulatesSnoNandSkiproteinexpression;promotesTGF-βsignaling,independentlyofMAPKactivation.Doesnotbindribosomesorblockproteinsynthesis.
| M.Wt | 513.55 |
| Formula | C24H31N7O6 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 22852-13-7 |
| PubChemID | 46173769 |
| InChIKey | LADKVYSQIGJMFP-IYRMOJGWSA-N |
| Smiles | O[C@@H]1[C@H](NC([C@@H](NC(C)=O)CC4=CC=C(OC)C=C4)=O)[C@@H](CO)O[C@H]1N3C2=NC=NC(N(C)C)=C2N=C3 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.HCl | 51.35 | 100 | |
| DMSO | 51.35 | 100 |
Thefollowingdataisbasedontheproductmolecularweight513.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.95mL | 9.74mL | 19.47mL |
| 5mM | 0.39mL | 1.95mL | 3.89mL |
| 10mM | 0.19mL | 0.97mL | 1.95mL |
| 50mM | 0.04mL | 0.19mL | 0.39mL |



