Cyclooxygenaseinhibitor;maybeselectiveforCOX-3(IC50valuesare460,>1000and>1000μMforcanineCOX-3,andmurineCOX-1andCOX-2respectively).Widelyusedanalgesicandantipyreticagent.
AcetaminophenisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 151.16 |
Formula | C8H9NO2 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 103-90-2 |
PubChemID | 1983 |
InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
Smiles | CC(=O)NC1=CC=C(O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
phosphatebufferedsaline | 7.56 | 50mMwithgentlewarming | |
DMSO | 15.12 | 100 | |
ethanol | 15.12 | 100 |
Thefollowingdataisbasedontheproductmolecularweight151.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 6.62mL | 33.08mL | 66.16mL |
5mM | 1.32mL | 6.62mL | 13.23mL |
10mM | 0.66mL | 3.31mL | 6.62mL |
50mM | 0.13mL | 0.66mL | 1.32mL |