Cyclooxygenaseinhibitor;maybeselectiveforCOX-3(IC50valuesare460,>1000and>1000μMforcanineCOX-3,andmurineCOX-1andCOX-2respectively).Widelyusedanalgesicandantipyreticagent.
AcetaminophenisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 151.16 |
| Formula | C8H9NO2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 103-90-2 |
| PubChemID | 1983 |
| InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
| Smiles | CC(=O)NC1=CC=C(O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| phosphatebufferedsaline | 7.56 | 50mMwithgentlewarming | |
| DMSO | 15.12 | 100 | |
| ethanol | 15.12 | 100 |
Thefollowingdataisbasedontheproductmolecularweight151.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 6.62mL | 33.08mL | 66.16mL |
| 5mM | 1.32mL | 6.62mL | 13.23mL |
| 10mM | 0.66mL | 3.31mL | 6.62mL |
| 50mM | 0.13mL | 0.66mL | 1.32mL |



