Competitivereversetranscriptaseinhibitor;inhibitsHIVreplication.Orallyactiveandbrainpenetrant.Antiretroviralagent.
SoldforresearchpurposesunderagreementfromViiv.
AbacavirhemisulfateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 335.37 |
Formula | C14H18N6O.½H2SO4 |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 188062-50-2 |
PubChemID | 75539558 |
InChIKey | WMHSRBZIJNQHKT-NHMRBCHTSA-N |
Smiles | OS(O)(=O)=O.NC1=NC(NC2CC2)=C2N=CN(C3C[C@H](CO)C=C3)C2=N1.NC1=NC(NC2CC2)=C2N=CN(C3C[C@H](CO)C=C3)C2=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 16.77 | 50 | |
water | 33.54 | 100 |
Thefollowingdataisbasedontheproductmolecularweight335.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.98mL | 14.91mL | 29.82mL |
5mM | 0.6mL | 2.98mL | 5.96mL |
10mM | 0.3mL | 1.49mL | 2.98mL |
50mM | 0.06mL | 0.3mL | 0.6mL |