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Tocris/ATC 0175 hydrochloride/3346/50/50 mg,Tocris,,Tocris,Tocris Bioscience,Tocris试剂采购 Tocris离子通道调控剂,,Array.Array.Array蚂蚁淘厂家直采.
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ATC 0175 hydrochloride/3346/50/50 mg
产品编号:3346/50
市  场 价:¥16900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$845.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ATC 0175 hydrochloride/3346/50/50 mg
商品介绍
Description:MCH1antagoNIST;also5-HT2Bantagonistand5-HT1Apartialagonist
ChemicalName:N-[cis-4-[[4-(Dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluorobenzamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveandorallyactivemelanin-concentratinghormonereceptor1(MCH1)antagonist(IC50valuesare13.5and>10000nMforMCH1andMCH2receptorsrespectively).Exhibitsanxiolyticandantidepressantactivityinrodents.Alsodisplaysaffinityfor5-HT2Band5-HT1Areceptors(IC50valuesare9.66and16.9nMrespectively).

TechnicalData

M.Wt461.94
FormulaC23H25F2N5O.HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber510733-97-8
PubChemID9934032
InChIKeyHUUPKFUYSQNNLO-UHFFFAOYSA-N
SmilesO=C(C4=CC(F)=C(F)C=C4)N[C@@H](CC3)CC[C@@H]3NC2=NC1=CC=CC=C1C(N(C)C)=N2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.6210
ethanol11.5525

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight461.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.16mL10.82mL21.65mL
5mM0.43mL2.16mL4.33mL
10mM0.22mL1.08mL2.16mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet