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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ARN 272/4574/10/10 mg
产品编号:4574/10
市  场 价:¥5580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$279.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ARN 272/4574/10/10 mg
商品介绍
Description:FAAH-likeanandamidetransporter(FLAT)inhibitor
ChemicalName:4-[[4-(4-Hydroxyphenyl)-1-phthalazinyl]amino]-N-phenylbenzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

FAAH-likeanandamidetransporter(FLAT)inhibitor(IC50=1.8μM);cytosolicvariantofFAAH-1thatbindsanandamide.Attenuatesanandamideinternalizationanddeactivationinvitroandinvivorespectively.ExhibitsanalgesiceffectsinrodentmodelsofCB1-mediatednociceptiveandinflammatorypain.

TechnicalData

M.Wt432.47
FormulaC27H20N4O2
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber488793-85-7
PubChemID24802717
InChIKeyYNADXFWEXJTQSZ-UHFFFAOYSA-N
SmilesOC(C=C4)=CC=C4C2=NN=C(NC3=CC=C(C(NC5=CC=CC=C5)=O)C=C3)C1=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.25100
ethanol8.6520

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight432.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.31mL11.56mL23.12mL
5mM0.46mL2.31mL4.62mL
10mM0.23mL1.16mL2.31mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet