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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AR-C 118925XX/4890/5/5 mg
产品编号:4890/5
市  场 价:¥5780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$289.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AR-C 118925XX/4890/5/5 mg
商品介绍
Description:Selective,competitiveP2Y2receptorantagoNIST
ChemicalName:5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective,competitiveP2Y2receptorantagonist.Inactiveagainstapanelof37otherreceptorsataconcentrationof10μM.InhibitsATP-γS-inducedmucinsecretioninbronchialepithelialcells(IC50=1μM).InhibitsP2Y2receptor-inducedβ-arrestintranslocationinvitro(pA2=37.2-51.3nM).

TechnicalData

M.Wt537.59
FormulaC28H23N7O3S
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber216657-60-2
PubChemID54210200
InChIKeyPVKNPGQAFNALOI-UHFFFAOYSA-N
SmilesCC(C=C1)=CC2=C1C(C3=CN(CC4=CC=C(C(NC5=NN=NN5)=O)O4)C(NC3=S)=O)C(C=CC(C)=C6)=C6C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO53.76100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight537.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.86mL9.3mL18.6mL
5mM0.37mL1.86mL3.72mL
10mM0.19mL0.93mL1.86mL
50mM0.04mL0.19mL0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet