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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AM 0902/5914/10/10 mg
产品编号:5914/10
市  场 价:¥2380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$119.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AM 0902/5914/10/10 mg
商品介绍
Description:PotentandselectiveTRPA1antagoNIST
ChemicalName:1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxADIazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveTRPA1antagonist(IC50=0.02μMforhumanTRPA1).ExhibitsnosiginificantactivityagainsthumanTRPV1orTRPV4,andratTRPV1,TRPV3orTRPM8.Exhibitsefficacyinaratpainmodel.Orallybioavailable.

TechnicalData

M.Wt370.79
FormulaC17H15ClN6O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1883711-97-4
PubChemID73297271
InChIKeyAWJBWNUUODWOKQ-UHFFFAOYSA-N
SmilesCN1C=NC2=C1C(N(C=N2)CC3=NC(CCC4=CC=C(C=C4)Cl)=NO3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.08100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight370.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.7mL13.48mL26.97mL
5mM0.54mL2.7mL5.39mL
10mM0.27mL1.35mL2.7mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet