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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AGK 2/3233/10/10 mg
产品编号:3233/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AGK 2/3233/10/10 mg
商品介绍
Description:SelectiveSIRT2inhibitor
ChemicalName:2-Cyano-3-[[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofSIRT2(IC50=3.5μM).DisplaysnoactivityatSIRT1andSIRT3atconcentrationsupto40μM.Reducesα-synuclein-mediatedtoxicityininvitroandinvivomodelsofParkinson'sdisease.

TechnicalData

M.Wt434.27
FormulaC23H13Cl2N3O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber304896-28-4
PubChemID2130404
InChIKeySVENPFFEMUOOGK-SDNWHVSQSA-N
SmilesO=C(/C(C#N)=C/C3=CC=C(C4=C(Cl)C=CC(Cl)=C4)O3)NC2=CC=CC1=NC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.3410

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight434.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.3mL11.51mL23.03mL
5mM0.46mL2.3mL4.61mL
10mM0.23mL1.15mL2.3mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet