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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AC 186/5053/50/50 mg
产品编号:5053/50
市  场 价:¥16900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$845.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AC 186/5053/50/50 mg
商品介绍
Description:PotentandselectiveERβagoNIST;neuroprotective
ChemicalName:4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveERβagonist(EC50valuesare6and5000nMforERβandERαrespectively).ExhibitsgenderselectiveneuroprotectiveeffectsinamaleratmodelofParkinson'sdisease.DecreasesAβlevelsincombinationwithACP-105inaratmodelofAlzheimer'sdisease.

CompoundLibraries

AC186isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt306.32
FormulaC18H17F3O
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber1421854-16-1
PubChemID71245042
InChIKeyHSMUKSLNDJOZQG-UHFFFAOYSA-N
SmilesFC1(F)CCC(C2=C(F)C=CC=C2)(C3=CC=C(O)C=C3)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.63100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight306.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.26mL16.32mL32.65mL
5mM0.65mL3.26mL6.53mL
10mM0.33mL1.63mL3.26mL
50mM0.07mL0.33mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet