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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ABT 724 trihydrochloride/2214/10/10 mg
产品编号:2214/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ABT 724 trihydrochloride/2214/10/10 mg
商品介绍
Description:Potent,selectiveD4partialagoNIST;proerectile
ChemicalName:2-[[4-(2-Pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazoletrihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentdopamineD4receptorpartialagonist(EC50=12.4nM;61%efficacyvs.dopamine).HasnoagonistactivityatD2receptors(EC50>10μM).Selectiveinratsinvivo;producespenileerectionfollowingi.c.v.administration;increasesintracavernosalpressureandpotentiatestheproerectileeffectsofsildenafilfollowings.c.administration.Displaysminimalsideeffects.

TechnicalData

M.Wt402.75
FormulaC17H19N5.3HCl
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber587870-77-7
PubChemID16759165
InChIKeyAZFUVPBLKQGSRI-UHFFFAOYSA-N
SmilesCl.Cl.Cl.C(N1CCN(CC1)C1=NC=CC=C1)C1=NC2=CC=CC=C2N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water40.27100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight402.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.48mL12.41mL24.83mL
5mM0.5mL2.48mL4.97mL
10mM0.25mL1.24mL2.48mL
50mM0.05mL0.25mL0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet