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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/A 784168/4319/50/50 mg
产品编号:4319/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/A 784168/4319/50/50 mg
商品介绍
Description:PotentandselectiveTRPV1antagoNIST
ChemicalName:3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTRPV1antagonist(IC50=25nMforinhibitionofTRPV1activationby50nMcapsaicin).Displaysnoactivityagainstarangeofreceptors,includingTRPA1,GABA,opioid,andpurinergicreceptors.

CompoundLibraries

A784168isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt479.4
FormulaC19H15F6N3O3S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber824982-41-4
PubChemID11420211
InChIKeySDUAWRFBHRAFBM-UHFFFAOYSA-N
SmilesO=C(NC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3)C(CC2)=CCN2C1=C(C(F)(F)F)C=CC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO47.94100
ethanol23.9750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight479.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.09mL10.43mL20.86mL
5mM0.42mL2.09mL4.17mL
10mM0.21mL1.04mL2.09mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet