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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/A 412997 dihydrochloride/4552/10/10 mg
产品编号:4552/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/A 412997 dihydrochloride/4552/10/10 mg
商品介绍
Description:SelectiveD4agoNIST
ChemicalName:N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveagonistforthedopamineD4receptor(Kivaluesare7.9and12.1nMforhumanD4andratD4receptors).Displaysnoaffinity(<1000nM)forotherdopaminereceptors.ShowsefficacyinratmodelsofADHDandshort-termmemory.

CompoundLibraries

A412997dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt382.33
FormulaC19H23N3O.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1347744-96-0
PubChemID90488953
InChIKeyKIGNSSHMCNBHQX-UHFFFAOYSA-N
SmilesO=C(CN2CCC(C3=CC=CC=N3)CC2)NC1=CC=CC(C)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO19.1250
ethanol1.915
water38.23100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight382.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.62mL13.08mL26.16mL
5mM0.52mL2.62mL5.23mL
10mM0.26mL1.31mL2.62mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet