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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/A 331440 dihydrochloride/4697/10/10 mg
产品编号:4697/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/A 331440 dihydrochloride/4697/10/10 mg
商品介绍
Description:SelectiveH3antagoNIST
ChemicalName:4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitriledihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityhistamineH3receptorantagonist(Kivaluesare21.7and22.7nMforratandhumanH3receptors,respectively).ExhibitsselectivityforhumanH3overH1,H2andH4receptors(Kivaluesare2940,14400and>10000nMrespectively).Showntoreduceweightinadiet-inducedobesitymodel.

TechnicalData

M.Wt422.39
FormulaC22H27N3O.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1049740-32-0
PubChemID16078942
InChIKeyXFPYVTSGYYMTFS-GHVWMZMZSA-N
SmilesCN(C)[C@H](CC3)CN3CCCOC1=CC=C(C2=CC=C(C#N)C=C2)C=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.4520
water42.24100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.84mL23.67mL
5mM0.47mL2.37mL4.73mL
10mM0.24mL1.18mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet