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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Fasentin/6100/50/50 mg
产品编号:6100/50
市  场 价:¥10100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$505.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Fasentin/6100/50/50 mg
商品介绍
Description:GLUT1/GLUT4inhibitor;alsoFas-sensitizer
ChemicalName:N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GLUT1andGLUT4inhibitor(IC50=68μM).PreferentiallyinhibitsGLUT4overGLUT1.SensitizesFasreceptorinarangeoftumorcelllines(IC50=20μM)bymodulatingtheextrinsicapoptoticpathwaydownstreamofTNFreceptorsbutupstreamofeffectorcaspases.

TechnicalData

M.Wt279.64
FormulaC11H9ClF3NO2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber392721-37-8
PubChemID879520
InChIKeyGNYIJZMBLZXJEJ-UHFFFAOYSA-N
SmilesCC(CC(NC1=CC(C(F)(F)F)=C(C=C1)Cl)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.96100
ethanol27.96100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight279.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.58mL17.88mL35.76mL
5mM0.72mL3.58mL7.15mL
10mM0.36mL1.79mL3.58mL
50mM0.07mL0.36mL0.72mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet