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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ST 034307/6271/50/50 mg
产品编号:6271/50
市  场 价:¥10900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$545.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ST 034307/6271/50/50 mg
商品介绍
Description:Adenylylcyclase1(AC1)inhibitor;analgesicandactiveinvivo
ChemicalName:6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Adenylylcyclase1(AC1)inhibitor(IC50=2.3μM).ExhibitssomeselectivityforAC1overotherACisoforms,withnosignificantactivityagainstAC8.InhibitsCa2+/calmodulin-stimulatedcAMPaccumulationinhippocampalhomogenates.Enhancesμopioidreceptor(MOR)-mediatedinhibitionofAC1incellularassaysandinhibitsdevelopmentandmaintenanceofMOR-mediatedsensitizationofAC1.Activeinvivo.Analgesic.

TechnicalData

M.Wt297.95
FormulaC10H4Cl4O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber133406-29-8
PubChemID867466
InChIKeyNTDHYMSVCBGQJF-UHFFFAOYSA-N
SmilesClC1=CC=C2OC(C(Cl)(Cl)Cl)=CC(C2=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.8100
ethanol5.9620

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight297.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.36mL16.78mL33.56mL
5mM0.67mL3.36mL6.71mL
10mM0.34mL1.68mL3.36mL
50mM0.07mL0.34mL0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet