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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ZCL 278/4794/10/10 mg
产品编号:4794/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ZCL 278/4794/10/10 mg
商品介绍
Description:Cdc42inhibitor
ChemicalName:2-(4-Bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]acetamide
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofCdc42.TargetsthebindingsiteoftheCdc42guaninenucleotideexchangefactor,intersectin(ITSN).InhibitsCdc42-mediatedcellulareffects,includingmicrospikeformationin3T3fibroblastsandneuronalbranchinginprimaryneonatalcorticalneurons.AlsosuppressescellmotilityandmigrationinPC3cells,withoutcytotoxiceffects.

CompoundLibraries

ZCL278isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt584.89
FormulaC21H19BrClN5O4S2
StorageStoreat+4°C
Purity≥95%(HPLC)
CASNumber587841-73-4
PubChemID1791111
InChIKeyXKZDWYDHEBCGCG-UHFFFAOYSA-N
SmilesClC1=C(OCC(NC(NC2=CC=C(S(NC3=NC(C)=CC(C)=N3)(=O)=O)C=C2)=S)=O)C=CC(Br)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO58.49100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight584.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.71mL8.55mL17.1mL
5mM0.34mL1.71mL3.42mL
10mM0.17mL0.85mL1.71mL
50mM0.03mL0.17mL0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet