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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/WWL 113/5259/50/50 mg
产品编号:5259/50
市  场 价:¥15100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$755.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/WWL 113/5259/50/50 mg
商品介绍
Description:Ces3andCes1finhibitor
ChemicalName:4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylicacidethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CarboxylesteraseCes3andCes1finhibitor(IC50valuesare~100nM).AlsoinhibitsABHD6.Exhibitsminimalactivityagainstapanelofotherserinehydrolases.PromoteslipidstorageinADIpocytes.Reducesweightgainindiet-inducedobesemiceandenhancesglucosetoleranceindiabeticmice.Orallyactive.

CompoundLibraries

WWL113isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt466.53
FormulaC29H26N2O4
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber947669-86-5
PubChemID17759482
InChIKeyAKIIPHDGVCFVCC-UHFFFAOYSA-N
SmilesCN(C(OC3=CC=C(C4=CC=C(C(OCC)=O)C=C4)C=C3)=O)CC1=CC=CC(C2=CC=NC=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.3350

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight466.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.14mL10.72mL21.43mL
5mM0.43mL2.14mL4.29mL
10mM0.21mL1.07mL2.14mL
50mM0.04mL0.21mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet