请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/VUF 10460/4769/50/50 mg
产品编号:4769/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/VUF 10460/4769/50/50 mg
商品介绍
Description:SelectiveH4agoNIST
ChemicalName:4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivehistamineH4receptoragonist;displays50-foldselectivityfortheratH4receptorovertheH3subtype(pKivaluesare5.75and7.46forratH3andH4receptorsrespectively).AlsoexhibitsaffinityforthehumanH4receptor(pKi=8.22).

CompoundLibraries

VUF10460isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt269.34
FormulaC15H19N5
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1028327-66-3
PubChemID25129523
InChIKeyNIJGWJIOMPHDBP-UHFFFAOYSA-N
SmilesNC1=NC(C2=CC=CC=C2)=CC(N3CCN(C)CC3)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
2eq.HCl26.93100
DMSO26.93100
ethanol26.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight269.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.71mL18.56mL37.13mL
5mM0.74mL3.71mL7.43mL
10mM0.37mL1.86mL3.71mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet