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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/UF 010/5588/10/10 mg
产品编号:5588/10
市  场 价:¥1300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$65.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/UF 010/5588/10/10 mg
商品介绍
Description:ClassIHDACinhibitor
ChemicalName:4-Bromo-N'-butylbenzohydrazide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ClassIHDACinhibitor(IC50valuesare0.06,0.1,0.5and1.5μMforHDACs3,2,1and8,respectively).Exhibits>6-foldselectivityoverotherHDACs.InducesaccumulationofacetylatedhistonesinHCT116cellsinvitro.Inhibitsproliferationofarangeofcancercelllines.ArrestscellsatG1/Stransition.

CompoundLibraries

UF010isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt271.15
FormulaC11H15BrN2O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber537672-41-6
PubChemID4596836
InChIKeyBVQCFCYPFJOOAV-UHFFFAOYSA-N
SmilesBrC1=CC=C(C(NNCCCC)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.11100
ethanol27.11100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight271.15.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.69mL18.44mL36.88mL
5mM0.74mL3.69mL7.38mL
10mM0.37mL1.84mL3.69mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet