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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TFM-4AS-1/3813/50/50 mg
产品编号:3813/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TFM-4AS-1/3813/50/50 mg
商品介绍
Description:Selectiveandrogenreceptormodulator(SARM)
ChemicalName:(1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-Trimethyl-7-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentselectiveandrogenreceptormodulator(SARM)(IC50=30nM).Steroidalcompound.Exhibitslimitedeffectsonreproductivetissuesandsebaceousglands;doesnotrepressAP-1-sensitiveMMP-1reporter.Inhibits5α-reductasetypeIandII(IC50valuesare2and3nMrespectively).

TechnicalData

M.Wt474.56
FormulaC27H33F3N2O2
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber188589-61-9
PubChemID10277123
InChIKeyYFBLEKKYWFJKBP-JZFZSVFHSA-N
SmilesO=C1C=C[C@@]2(C)[C@](CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](NC5=C(C(F)(F)F)C=CC=C5)=O)([H])N1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.7510
ethanol4.7510

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight474.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.11mL10.54mL21.07mL
5mM0.42mL2.11mL4.21mL
10mM0.21mL1.05mL2.11mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet