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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TCS 359/2591/50/50 mg
产品编号:2591/50
市  场 价:¥12580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>激酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$629.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TCS 359/2591/50/50 mg
商品介绍
Description:PotentFLT3inhibitor
ChemicalName:2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofFLT3receptortyrosinekinase(IC50=42nM)thatdisplaysselectivityoverarangeofotherkinases.ExhibitsantiproliferativeeffectsonMV4-11cells,ahumanacutemyelogenousleukemiacelllineexpressingaconstitutivelyactivemutantFLT3(IC50=340nM).

CompoundLibraries

TCS359isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt360.43
FormulaC18H20N2O4S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber301305-73-7
PubChemID1048845
InChIKeyFSPQCTGGIANIJZ-UHFFFAOYSA-N
SmilesCOC1=CC=C(C=C1OC)C(=O)NC1=C(C(N)=O)C2=C(CCCC2)S1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.8130

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight360.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.77mL13.87mL27.74mL
5mM0.55mL2.77mL5.55mL
10mM0.28mL1.39mL2.77mL
50mM0.06mL0.28mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet