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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC-G 1008/5355/50/50 mg
产品编号:5355/50
市  场 价:¥16100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$805.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC-G 1008/5355/50/50 mg
商品介绍
Description:PotentandselectiveGPR39agoNIST
ChemicalName:N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGPR39agonist(EC50valuesare0.4and0.8nMforratandhumanreceptorsrespectively).Selectiveoverapanelofkinases(IC50s>10μM)anddisplaysminimalbindingaffinityforghrelinandneurotensin-1receptors(IC50s>30μM).IncreasesGLP-1levelsinvitroandinvivo.Orallybioavailable.

CompoundLibraries

TC-G1008isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt418.9
FormulaC18H19ClN6O2S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1621175-65-2
PubChemID91826086
InChIKeyDRSZMILOMUPIBJ-UHFFFAOYSA-N
SmilesCNC1=NC(NCC2=C(Cl)C=C(NS(C)(=O)=O)C=C2)=CC(C3=NC=CC=C3)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.89100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.9.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.39mL11.94mL23.87mL
5mM0.48mL2.39mL4.77mL
10mM0.24mL1.19mL2.39mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet