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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC-G 1006/4747/10/10 mg
产品编号:4747/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC-G 1006/4747/10/10 mg
商品介绍
Description:Potentandselectivesphingosine-1-phosphatereceptor1(S1P1)agoNIST
ChemicalName:4-Methoxy-N-[[[2-trifluoromethyl)[1,1'-biphenyl]-4-yl]amino]carbonyl]-3-pyridinecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivesphingosine-1-phosphatereceptor1(S1P1)agonist(EC50=35nM),displays>100-foldselectivityagainstreceptorsubtypesS1P2-5.Inducesadose-dependentreductionincirculatingbloodlymphocytecountsinrodentmodels.Orallybioavailable.

CompoundLibraries

TC-G1006isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt415.37
FormulaC21H16F3N3O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1324003-64-6
PubChemID54764919
InChIKeyMLDQTQOMWDNTNN-UHFFFAOYSA-N
SmilesO=C(NC(C2=C(OC)C=CN=C2)=O)NC1=CC=C(C3=CC=CC=C3)C(C(F)(F)F)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight415.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.41mL12.04mL24.07mL
5mM0.48mL2.41mL4.81mL
10mM0.24mL1.2mL2.41mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet