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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC-G 1005/5129/10/10 mg
产品编号:5129/10
市  场 价:¥4100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$205.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC-G 1005/5129/10/10 mg
商品介绍
Description:PotentandselectiveGPBAreceptor(TGR5)agoNIST
ChemicalName:(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGPBAagonist(EC50=0.72nMforhTGR5).SelectiveforTGR5overFXR(farnesoidXreceptor).IncreasesplasmaGLP-1levelsandreducesbloodglucoseinmice.Orallyavailable.

CompoundLibraries

TC-G1005isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt399.48
FormulaC25H25N3O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1415407-60-1
PubChemID71450251
InChIKeyJQULIQJSYPZQMA-UHFFFAOYSA-N
SmilesCC1=CC(OC2=CC=NC=C2C(N3C(C=CC=C4)=C4N(C5CC5)CC3)=O)=C(C)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.95100
ethanol39.95100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight399.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.5mL12.52mL25.03mL
5mM0.5mL2.5mL5.01mL
10mM0.25mL1.25mL2.5mL
50mM0.05mL0.25mL0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet