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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/TC-F 2/4355/50/50 mg
产品编号:4355/50
市  场 价:¥17580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$879.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/TC-F 2/4355/50/50 mg
商品介绍
Description:Potent,reversIBLeandselectiveFAAHinhibitor
ChemicalName:1-[(3S)-1-[4-(2-Benzofuranyl)-2-pyrimidinyl]-3-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,reversibleinhibitoroffattyacidamidehydrolase(FAAH)(IC50valuesare28and100nMforhumanandratFAAHrespectively).Noncovalentinhibitor;displaysselectivityforFAAHovercannABInoid-relatedtargets(IC50>20μMforCB1,CB2andTRPV1).Activeinvivo.

CompoundLibraries

TC-F2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt439.51
FormulaC26H25N5O2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber1304778-15-1
PubChemID25198728
InChIKeyNXTBLPPTZRPJCA-IBGZPJMESA-N
SmilesO=C(N(CC)C6=C5C=CC=C6)N5[C@H]1CCCN(C2=NC(C3=CC(C=CC=C4)=C4O3)=CC=N2)C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.95100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight439.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.28mL11.38mL22.75mL
5mM0.46mL2.28mL4.55mL
10mM0.23mL1.14mL2.28mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet