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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SecinH3/2849/10/10 mg
产品编号:2849/10
市  场 价:¥4500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>球蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$225.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SecinH3/2849/10/10 mg
商品介绍
Description:Sec7-specificGEFinhibitor(cytohesins)
ChemicalName:N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Sec7-specificGEFinhibitorthatdisplaysselectivityforsmallGEFsofthecytohesinfamily(IC50valuesare2.4,5.4,5.4,5.6,5.6,65and>100μMforhCyh4,hCyh1,mCyh3,hCyh3,drosophilasteppke,yGea2-S7andhEFA6-S7respectively).Inhibitsinsulinsignalingviainhibitionofinsulinreceptorsubstrateprotein(IRS)phosphorylation.

TechnicalData

M.Wt460.5
FormulaC24H20N4O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber853625-60-2
PubChemID1029232
InChIKeyQPGYAMIHXLCFTJ-UHFFFAOYSA-N
SmilesO=C(CSC5=CC=CC=C5)NC(C=C4)=CC=C4N1C(C2=CC(OCO3)=C3C=C2)=NC(OC)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.05100
ethanol4.6110mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight460.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.17mL10.86mL21.72mL
5mM0.43mL2.17mL4.34mL
10mM0.22mL1.09mL2.17mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet