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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SR 12813/2969/50/50 mg
产品编号:2969/50
市  场 价:¥9100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$455.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SR 12813/2969/50/50 mg
商品介绍
Description:PregnaneXreceptoragoNIST
ChemicalName:[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PregnaneXreceptor(PXR)agonist(EC50valuesare200and700nMforhumanandrabbitPXRrespectively).ActivatesthefarnesoidXreceptor(FXR)atμMconcentrations.DisplayshypocholesterolaemicactivityviaenchanceddegradationofHMG-CoAreductase.

TechnicalData

M.Wt504.53
FormulaC24H42O7P2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber126411-39-0
PubChemID446313
InChIKeyYQLJDECYQDRSBI-UHFFFAOYSA-N
SmilesOC1=C(C(C)(C)C)C=C(/C=C(P(OCC)(OCC)=O)/P(OCC)(OCC)=O)C=C1C(C)(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO50.45100
ethanol50.45100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight504.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.98mL9.91mL19.82mL
5mM0.4mL1.98mL3.96mL
10mM0.2mL0.99mL1.98mL
50mM0.04mL0.2mL0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet