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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SMER 28/4297/10/10 mg
产品编号:4297/10
市  场 价:¥2180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$109.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SMER 28/4297/10/10 mg
商品介绍
Description:Positiveregulatorofautophagy
ChemicalName:6-Bromo-N-2-propenyl-4-quinazolinamine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PositiveregulatorofautophagyinamechanismindependentfromthemTORpathway.IncreasesautophagosomesynthesisandenhancesclearanceofmodelautophagysubstratessuchasmutanthuntingtinandA53Tα-synuclein,associatedwithHuntington'sandParkinson'sdiseases,respectively.Promotesreprogrammingoffibroblaststoneuralstem-likecellsincombinationwithotherchemicalreagents.

CompoundLibraries

SMER28isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt264.12
FormulaC11H10BrN3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber307538-42-7
PubChemID1560402
InChIKeyBCPOLXUSCUFDGE-UHFFFAOYSA-N
SmilesC=CCNC2=NC=NC1=CC=C(Br)C=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
ethanol(suppliedpre-dissolvedinabsoluteethanol,27µg/ml)13.2150
DMSO26.41100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight264.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.79mL18.93mL37.86mL
5mM0.76mL3.79mL7.57mL
10mM0.38mL1.89mL3.79mL
50mM0.08mL0.38mL0.76mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet