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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AM 4113/6193/50/50 mg
产品编号:6193/50
市  场 价:¥10500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$525.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AM 4113/6193/50/50 mg
商品介绍
Description:Selective,highaffinityCB1antagoNIST
ChemicalName:5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityandselectiveCB1antagonist(Kd=0.89nM).Exhibits100-foldselectivityforCB1overCB2.AttenuatesCB1agonistAM411-inducedlocomotorsuppressionandreducesfoodintakeinvivo,butdoesnotinducesignsofnausea.

TechnicalData

M.Wt380.66
FormulaC17H12Cl3N3O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber614726-85-1
PubChemID66844170
InChIKeyBBUKVPCUOHFAQN-UHFFFAOYSA-N
SmilesCC1=C(C2=CC=C(C=C2)Cl)N(C3=C(C=C(C=C3)Cl)Cl)N=C1C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO7.6120
ethanol7.6120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight380.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.63mL13.14mL26.27mL
5mM0.53mL2.63mL5.25mL
10mM0.26mL1.31mL2.63mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet