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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SANT-2/3617/10/10 mg
产品编号:3617/10
市  场 价:¥3700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SANT-2/3617/10/10 mg
商品介绍
Description:InhibitorofHedgehog(Hh)signaling;antagonizessmoothenedactivity
ChemicalName:N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofSonichedgehog(Shh)signaling;antagonizessmoothenedreceptoractivity(KD=12nM).DisplaysallostericbindingcharacteristicssimilartoSANT-1(Cat.No.1974).Displacessmo-[3H]SAG-1.3and-[3H]Cyclopaminebinding(Kivaluesare7.8nMand8.4nMrespectively).

CompoundLibraries

SANT-2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt479.96
FormulaC26H26ClN3O4
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber329196-48-7
PubChemID1367095
InChIKeyVQOJFGFKIVFMDH-UHFFFAOYSA-N
SmilesClC1=CC=C(NC(C4=CC(OCC)=C(OCC)C(OCC)=C4)=O)C=C1C3=NC2=CC=CC=C2N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO48100
ethanol48100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight479.96.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.08mL10.42mL20.84mL
5mM0.42mL2.08mL4.17mL
10mM0.21mL1.04mL2.08mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet