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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/SANT-1/1974/50/50 mg
产品编号:1974/50
市  场 价:¥14180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$709.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/SANT-1/1974/50/50 mg
商品介绍
Description:Inhibitorofhedgehog(Hh)signaling;antagonizessmoothenedactivity
ChemicalName:N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,cell-permeableinhibitorofSonichedgehog(Shh)signaling;highaffinityantagoNISTofsmoothenedactivity(KD=1.2nM).InhibitssmoothenedagonisteffectswithanIC50of20nM(inShh-LIGHT2cells).

CompoundLibraries

SANT-1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt373.5
FormulaC23H27N5
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber304909-07-7
PubChemID6878030
InChIKeyFOORCIAZMIWALX-JJIBRWJFSA-N
SmilesCC1=NN(C(C)=C1C=NN1CCN(CC2=CC=CC=C2)CC1)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.6850
ethanol9.3425

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight373.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.68mL13.39mL26.77mL
5mM0.54mL2.68mL5.35mL
10mM0.27mL1.34mL2.68mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet