请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Rotenone/3616/50/50 mg
产品编号:3616/50
市  场 价:¥1180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Rotenone/3616/50/50 mg
商品介绍
Description:InhibitscomplexIofthemitochondrialelectrontransportchain
ChemicalName:(2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Mitochondrialelectrontransportchaininhibitor(IC50=1.7-2.2μMatcomplexI).InhibitsNADHoxidationbycardiacsarcoplasmicreticulum(IC50=3.4nM).CommonlyusedpesticideandinducesParkinsonisminanimalmodels.Mayalsoinhibitautophagyinduction;blockslysosomaldegradationofautophagicvacuoles.Cell-permeableandbrainpenetrant.

TechnicalData

M.Wt394.42
FormulaC23H22O6
StorageStoreatRT
Purity≥95%(HPLC)
CASNumber83-79-4
PubChemID6758
InChIKeyJUVIOZPCNVVQFO-HBGVWJBISA-N
SmilesC=[C@](C)[C@@H](C5)OC4=C5C(O3)=C(C=C4)C([C@@]([C@@]3([H])CO2)([H])C1=C2C=C(OC)C(OC)=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.44100
ethanol1.975

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight394.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.54mL12.68mL25.35mL
5mM0.51mL2.54mL5.07mL
10mM0.25mL1.27mL2.54mL
50mM0.05mL0.25mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet