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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ro 32-3555/2916/10/10 mg
产品编号:2916/10
市  场 价:¥5180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$259.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ro 32-3555/2916/10/10 mg
商品介绍
Description:Potent,Collagenase-selectiveMMPinhibitor
ChemicalName:(αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidiNEButanamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,collagenase-selectiveMMPinhibitor(Kivaluesare3.0,3.4,4.4,59,154and527nMforMMP-1,MMP-13,MMP-8,MMP-9,MMP-2andMMP-3respectively).Inhibitscartilagebreakdowninvitroandinvivoanddisplaysantiarthriticactivity.Orallyactive.

TechnicalData

M.Wt436.55
FormulaC22H36N4O5
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber190648-49-8
PubChemID9824350
InChIKeyGFUITADOEPNRML-SJORKVTESA-N
SmilesO=[C@@](N3CCCCC3)[C@H](CC1CCCC1)[C@@H]([C@](NO)=O)CN2C(N(C)C(C)(C)C2=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.66100
ethanol43.66100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight436.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.29mL11.45mL22.91mL
5mM0.46mL2.29mL4.58mL
10mM0.23mL1.15mL2.29mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet