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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ritonavir/5856/50/50 mg
产品编号:5856/50
市  场 价:¥1980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$99.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ritonavir/5856/50/50 mg
商品介绍
Description:HIV-1andHIV-2proteaseinhibitor
AlternativeNames:ABT-538,A-84538,Abbot84538
ChemicalName:5-Thiazolylmethyl(3S,4S,6S,9S)-4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HIV-1andHIV-2proteaseinhibitor(EC50valuesare0.022-0.13and0.16μM,respectively).BlocksthemetabolismofproteaseinhibitorsbyliverenzymecytochromeP450-3A4(CYP3A4).Orallybioavailable.

TechnicalData

M.Wt720.94
FormulaC37H48N6O5S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber155213-67-5
PubChemID392622
InChIKeyNCDNCNXCDXHOMX-XGKFQTDJSA-N
SmilesO[C@@H](C[C@@H](NC([C@H](C(C)C)NC(N(C)CC1=CSC(C(C)C)=N1)=O)=O)CC2=CC=CC=C2)[C@@H](NC(OCC3=CN=CS3)=O)CC4=CC=CC=C4

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO14.4220mMwithgentlewarming
ethanol7.2110

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight720.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.39mL6.94mL13.87mL
5mM0.28mL1.39mL2.77mL
10mM0.14mL0.69mL1.39mL
50mM0.03mL0.14mL0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet