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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Resiquimod/4536/10/10 mg
产品编号:4536/10
市  场 价:¥1780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$89.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Resiquimod/4536/10/10 mg
商品介绍
Description:Toll-likereceptor7(TLR7)agoNIST
AlternativeNames:R848
ChemicalName:1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Toll-likereceptor7(TLR7)agonist.InducesupregulationofIL-6,IL-12,IFN-γandiNOSexpressioninmousebonemarrow-derivedmacrophages(BMMs).InhibitsRANKL-inducedosteoclastdifferentiationinmouseBMMsandhumanperipheralbloodmonocytes.AlsopromotesthedifferentiationofMDSCsintomacrophagesanddendriticcells.Proinflammatoryandantiviral.

CompoundLibraries

ResiquimodisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt314.38
FormulaC17H22N4O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber144875-48-9
PubChemID159603
InChIKeyBXNMTOQRYBFHNZ-UHFFFAOYSA-N
SmilesNC1=C3C(N(CC(C)(O)C)C(COCC)=N3)=C2C(C=CC=C2)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.44100
ethanol15.7250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight314.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.18mL15.9mL31.81mL
5mM0.64mL3.18mL6.36mL
10mM0.32mL1.59mL3.18mL
50mM0.06mL0.32mL0.64mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet