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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ranolazine dihydrochloride/3118/50/50 mg
产品编号:3118/50
市  场 价:¥2300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$115.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ranolazine dihydrochloride/3118/50/50 mg
商品介绍
Description:Antianginal,activatespyruvatedehydrogenase
AlternativeNames:RS43285
ChemicalName:N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamidedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antianginalagentwithantiarrhythmicpropertiesthatactsasapartialfattyacidoxidationinhibitor.Activatespyruvatedehydrogenaseinischemicmyocytestopromoteglucoseoxidation,switchingsubstrateutilizationfromfattyacidstoglucose.AlsoshowntoinhibitlateINaandIKrcurrents.

CompoundLibraries

RanolazinedihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt500.46
FormulaC24H33N3O4.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber95635-56-6
PubChemID71279
InChIKeyRJNSNFZXAZXOFX-UHFFFAOYSA-N
SmilesCOC1=CC=CC=C1OCC(CN2CCN(CC(NC3=C(C)C=CC=C3C)=O)CC2)O.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO50.05100
water50.05100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight500.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2mL9.99mL19.98mL
5mM0.4mL2mL4mL
10mM0.2mL1mL2mL
50mM0.04mL0.2mL0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet