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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/RWJ 50271/4227/50/50 mg
产品编号:4227/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/RWJ 50271/4227/50/50 mg
商品介绍
Description:InhibitorofLFA-1/ICAMmediatedcelladhesion
ChemicalName:N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofLFA-1(lymphocytefunction-associatedantigen-1)adhesiontosolubleintercellularadhesionmolecule(sICAM)(IC50=5μMinHL60cells).

CompoundLibraries

RWJ50271isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt410.41
FormulaC18H17F3N4O2S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber162112-37-0
PubChemID9953357
InChIKeyHOFGTYCLOKDAES-UHFFFAOYSA-N
SmilesCC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.04100
ethanol4.110

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight410.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.44mL12.18mL24.37mL
5mM0.49mL2.44mL4.87mL
10mM0.24mL1.22mL2.44mL
50mM0.05mL0.24mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet