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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/RETRA hydrochloride/3214/50/50 mg
产品编号:3214/50
市  场 价:¥12900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$645.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/RETRA hydrochloride/3214/50/50 mg
商品介绍
Description:Antitumoragent;suppressesmutantp53-bearingcancercells
ChemicalName:2-[(4,5-Dihydro-2-thiazolyl)thio]-1-(3,4-dihydroxyphenyl)ethanonehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antitumoragent.Inhibitstumorcellgrowthinamutantp53-andp73-dependentmannerinvitroandinvivo(IC50=4μM).Transcriptionallyactivatesexpressionofp53-responsivegenesandinducesactivationofeffectorcaspases3and7.

TechnicalData

M.Wt305.8
FormulaC11N11NO3S2.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber1173023-52-3
PubChemID46861546
InChIKeyZZAVDVMJZKDBIB-UHFFFAOYSA-N
SmilesOC1=CC(C(CSC2=NCCS2)=O)=CC=C1O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.58100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight305.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.27mL16.35mL32.7mL
5mM0.65mL3.27mL6.54mL
10mM0.33mL1.64mL3.27mL
50mM0.07mL0.33mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet