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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/RBC8/5411/50/50 mg
产品编号:5411/50
市  场 价:¥19300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$965.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/RBC8/5411/50/50 mg
商品介绍
Description:RalAandRalBGTPaseinhibitor
ChemicalName:6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RalAandRalBGTPaseinhibitor(EC50~3.5μM).InhibitsthebindingofRaltoRaLBP1.ExhibitsnodetectableinhibitionofRasorRhoAactivity.Suppressesgrowthofxenografttumorsinmice.Cellpermeable.

CompoundLibraries

RBC8isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt424.45
FormulaC25H20N4O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber361185-42-4
PubChemID6626226
InChIKeyCLMQBVUFKIKYLU-UHFFFAOYSA-N
SmilesNC1=C(C#N)C(C5=C(OC)C=CC(OC)=C5)C(C(C3=CC=C(C=CC=C4)C4=C3)=NN2)=C2O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.44100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight424.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.36mL11.78mL23.56mL
5mM0.47mL2.36mL4.71mL
10mM0.24mL1.18mL2.36mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet