请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/R 7050/5432/10/10 mg
产品编号:5432/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/R 7050/5432/10/10 mg
商品介绍
Description:InhibitorofTNF-αreceptor1signaling
ChemicalName:8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofTNF-αreceptor1(TNFR1)signaling;blocksTNFR1associationwithTRADDandRIP1.InhibitsTNF-α-inducedNF-κBandMAPKsignalingpathwayactivation.Attenuatesintracerebralhemorrhage-inducedneurovascularinjuryinmice.

TechnicalData

M.Wt380.77
FormulaC16H8ClF3N4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber303997-35-5
PubChemID1486608
InChIKeySUUMKHOVGVYGOP-UHFFFAOYSA-N
SmilesClC1=CC=C(N=C(SC4=CC=CC=C4)C2=NN=C(C(F)(F)F)N23)C3=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO7.6220

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight380.77.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.63mL13.13mL26.26mL
5mM0.53mL2.63mL5.25mL
10mM0.26mL1.31mL2.63mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet