请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Pitavastatin calcium/4942/50/50 mg
产品编号:4942/50
市  场 价:¥8900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$445.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Pitavastatin calcium/4942/50/50 mg
商品介绍
Description:HMG-CoAreductaseinhibitor
AlternativeNames:NK-104
ChemicalName:(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoicacidhemicalciumsalt
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SyntheticinhibitorofHMG-CoAreductase(Ki=1.7nM).Lowerslow-densitylipoprotein(LDL)cholesterollevels.DisplaysminimalmetabolismbycytochromeP450enzymes,withlittleinvolvementofCYP3A4.Showntoimprovecardiacfunctionandsurvivalinaratmodelofhypertensiveheartfailure.

CompoundLibraries

PitavastatincalciumisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt440.5
FormulaC25H23FNO4.0.5Ca
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber147526-32-7
PubChemID5282451
InChIKeyRHGYHLPFVJEAOC-FFNUKLMVSA-L
Smiles[Ca++].O[C@H](C[C@H](O)C=CC1=C(C2=CC=C(F)C=C2)C2=CC=CC=C2N=C1C1CC1)CC([O-])=O.O[C@H](C[C@H](O)C=CC1=C(C2=CC=C(F)C=C2)C2=CC=CC=C2N=C1C1CC1)CC([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO44.05100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight440.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.35mL22.7mL
5mM0.45mL2.27mL4.54mL
10mM0.23mL1.14mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet