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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PR 619/4482/50/50 mg
产品编号:4482/50
市  场 价:¥7500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$375.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PR 619/4482/50/50 mg
商品介绍
Description:BroadspectrumDUBinhibitor
ChemicalName:2,6-Diamino-3,5-dithiocyanopyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Broadspectrum,reversIBLeDUBinhibitor.Exhibitslimitedactivityagainstotherproteases.Inducesaccumulationofpolyubiquitinatedproteins,buthasnodirectinhibitoryeffectontheproteasome.CytotoxicinHEK293Tandcolorectalcancercells.StABIlizesmicrotubulenetworkinoligodendroglialcells.

TechnicalData

M.Wt223.28
FormulaC7H5N5S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber2645-32-1
PubChemID2817763
InChIKeyZXOBLNBVNROVLC-UHFFFAOYSA-N
SmilesNC1=C(SC#N)C=C(SC#N)C(N)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO2.2310

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight223.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.48mL22.39mL44.79mL
5mM0.9mL4.48mL8.96mL
10mM0.45mL2.24mL4.48mL
50mM0.09mL0.45mL0.9mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet