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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PPT/1426/50/50 mg
产品编号:1426/50
市  场 价:¥14180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$709.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PPT/1426/50/50 mg
商品介绍
Description:Subtype-selectiveERαagoNIST
ChemicalName:4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,subtype-selectiveestrogenreceptoragonist(EC50~200pM);displays410-foldselectivityforERαoverERβ.Preventsovariectomy-inducedweightgainandlossofbonemineraldensity,andinducesgeneexpressioninthehypothalamusfollowingsystemicadministrationinvivo.

CompoundLibraries

PPTisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt386.45
FormulaC24H22N2O3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber263717-53-9
PubChemID6095481
InChIKeyUOSWGERPQQOSHS-UHFFFAOYSA-N
SmilesCCCC1=C(N(N=C1C1=CC=C(O)C=C1)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.65100
ethanol1.935

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight386.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.59mL12.94mL25.88mL
5mM0.52mL2.59mL5.18mL
10mM0.26mL1.29mL2.59mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet