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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/WZB 117/6143/25/25 mg
产品编号:6143/25
市  场 价:¥6180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$309.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/WZB 117/6143/25/25 mg
商品介绍
Description:GLUTinhibitor
ChemicalName:3-Fluoro-1,2-phenylenebis(3-hydroxybenzoate)
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GLUTinhibitor(Ki(app)valuesare0.2,10and10μMforGLUT4,GLUT1andGLUT3,respectively).Competitiveinhibitorofnetglucoseuptakebutanoncompetitiveinhibitorofsugareffluxfromcells.Inhibitspassivesugartransportinhumanerythrocytesandcancercelllines.Attenuateserythrocyte3-O-metylglucose(3MG)uptakeinvitro(Ki=6μM).Suppressestumorgrowthinanudemousemodel.

TechnicalData

M.Wt368.31
FormulaC20H13FO6
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1223397-11-2
PubChemID46830365
InChIKeyFRSWCCBXIHFKKY-UHFFFAOYSA-N
SmilesOC1=CC=CC(C(OC2=C(C(F)=CC=C2)OC(C3=CC(O)=CC=C3)=O)=O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO36.83100
ethanol36.83100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight368.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.72mL13.58mL27.15mL
5mM0.54mL2.72mL5.43mL
10mM0.27mL1.36mL2.72mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet