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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/OAC-1/4887/10/10 mg
产品编号:4887/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/OAC-1/4887/10/10 mg
商品介绍
Description:Oct4activator;enhancesiPSCreprogrammingefficiency
ChemicalName:N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Oct4activator.EnhancesandacceleratesiPSCreprogramminginthepresenceof4F(Oct4,Sox2,c-MycandKlf4)by~20-foldcomparedto4Falone.InducesmRNAexpressionofOct4,Sox2andNanogandalsoTet1.Displaysnoeffectsonp53-p21pathwayorWnt-β-cateninsignaling.

CompoundLibraries

OAC-1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt237.26
FormulaC14H11N3O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber300586-90-7
PubChemID789882
InChIKeyHWJRIFZDXJKJJN-UHFFFAOYSA-N
SmilesO=C(C3=CC=CC=C3)NC1=NC=C2C(C=CN2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.73100
ethanol23.73100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight237.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.21mL21.07mL42.15mL
5mM0.84mL4.21mL8.43mL
10mM0.42mL2.11mL4.21mL
50mM0.08mL0.42mL0.84mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet