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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Necrosulfonamide/5025/50/50 mg
产品编号:5025/50
市  场 价:¥7980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$399.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Necrosulfonamide/5025/50/50 mg
商品介绍
Description:Necroptosisinhibitor
ChemicalName:(2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Necroptosisinhibitor.Blocksmixedlineagekinasedomain-likeprotein(MLKL),acriticalsubstrateofreceptor-interactingserine-threoninekinase3(RIP3)duringnecrosis.PreventsMLKL-RIP1-RIP3necrosomecomplexfrominteractingwithdownstreamnecrosiseffectors.

TechnicalData

M.Wt461.47
FormulaC18H15N5O6S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1360614-48-7
PubChemID1566236
InChIKeyFNPPHVLYVGMZMZ-XBXARRHUSA-N
SmilesO=C(NC2=CC=C(S(NC3=C(OC)N=CC=N3)(=O)=O)C=C2)/C=C/C1=CC=C([N+]([O-])=O)S1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.2320

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight461.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.17mL10.83mL21.67mL
5mM0.43mL2.17mL4.33mL
10mM0.22mL1.08mL2.17mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet