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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NSC 668036/5813/10/10 mg
产品编号:5813/10
市  场 价:¥2900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$145.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NSC 668036/5813/10/10 mg
商品介绍
Description:Wntsignalinginhibitor;bindsthePDZdomainoftheDishevelled(Dvl)protein
ChemicalName:N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Wntsignalinginhibitor.BindsthePDZdomainoftheDishevelled(Dvl)protein.Inhibitsproliferation,migrationandTGF-β-induceddifferentiationoffibroblastsinvitro.Reducesseverityofpulmonaryfibrosisinamousemodel.

TechnicalData

M.Wt460.52
FormulaC21H36N2O9
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber144678-63-7
PubChemID71312060
InChIKeyIPICFSFUAKDZEI-AJNGGQMLSA-N
SmilesCC([C@@H](C(O)=O)OC([C@@H](NC([C@H](C(C)C)OC([C@@H](NC(OC(C)(C)C)=O)C)=O)=O)C)=O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.05100
ethanol46.05100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight460.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.17mL10.86mL21.71mL
5mM0.43mL2.17mL4.34mL
10mM0.22mL1.09mL2.17mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet