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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NSC 146109 hydrochloride/2185/50/50 mg
产品编号:2185/50
市  场 价:¥11700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$585.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NSC 146109 hydrochloride/2185/50/50 mg
商品介绍
Description:Cell-permeable,genotype-selectiveantitumoragent;activatesp53-dependenttranscription
ChemicalName:(10-Methyl-9-anthracenyl)methylcarbamimidothioicacidesterhydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeable,genotype-selectiveantitumoragentthatactivatesp53-dependenttranscription.Increaseslevelsofendogenousp53intumorcellsandprotectsp53fromMdm2-mediateddegradation.Displayssomeselectivityfortumorcellsvs.normalcellsinanMTTcellviABIlityassay.

TechnicalData

M.Wt316.85
FormulaC17H16N2S.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber59474-01-0
PubChemID5458312
InChIKeyVIBMUYOXJUCEMA-UHFFFAOYSA-N
SmilesN=C(N)SCC1=C(C=CC=C3)C3=C(C)C2=C1C=CC=C2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.68100
ethanol3.1710

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight316.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.16mL15.78mL31.56mL
5mM0.63mL3.16mL6.31mL
10mM0.32mL1.58mL3.16mL
50mM0.06mL0.32mL0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet