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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NBD 556/5811/10/10 mg
产品编号:5811/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 其它>其它试剂>临床研究>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NBD 556/5811/10/10 mg
商品介绍
Description:CD4mimetic;blocksHIV-1cellentry
ChemicalName:N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CD4mimetic(IC50valuesareinlowmicromolarrange,dependentoncelltypeandHIVstrain).RecognizesandinducesstructuralchangesinHIV-1envelopeproteingp120,analogoustoCD4binding.InhibitsHIV-1cellentryinCXCR4andCCR5expressingcelllines,byblockingvirus-cellandcell-cellfusion.

TechnicalData

M.Wt337.84
FormulaC17H24ClN3O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber333353-44-9
PubChemID1570601
InChIKeyZKXLQCIOURANAD-UHFFFAOYSA-N
SmilesCC1(CC(NC(C(NC2=CC=C(C=C2)Cl)=O)=O)CC(C)(N1)C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.78100
ethanol6.7620

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight337.84.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.96mL14.8mL29.6mL
5mM0.59mL2.96mL5.92mL
10mM0.3mL1.48mL2.96mL
50mM0.06mL0.3mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet